6 CFR § 46.113 - Suspension or termination of IRB approval of research.

---
identifier: "/us/cfr/t6/s46.113"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "6 CFR § 46.113 - Suspension or termination of IRB approval of research."
title_number: 6
title_name: "Domestic Security"
section_number: "46.113"
section_name: "Suspension or termination of IRB approval of research."
chapter_name: "DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY"
part_number: "46"
part_name: "PROTECTION OF HUMAN SUBJECTS"
positive_law: false
currency: "2026-03-24"
last_updated: "2026-03-24"
format_version: "1.1.0"
generator: "[email protected]"
authority: "5 U.S.C. 301; Pub. L. 107-296, sec. 102, 306(c); Pub. L. 108-458, sec. 8306."
regulatory_source: "82 FR 7269, Jan. 19, 2017, unless otherwise noted."
cfr_part: "46"
---


# 46.113 Suspension or termination of IRB approval of research.

An IRB shall have authority to suspend or terminate approval of research that is not being conducted in accordance with the IRB's requirements or that has been associated with unexpected serious harm to subjects. Any suspension or termination of approval shall include a statement of the reasons for the IRB's action and shall be reported promptly to the investigator, appropriate institutional officials, and the department or agency head.

(Approved by the Office of Management and Budget under Control Number 0990-0260)