21 CFR § 173.220 - 1,3-Butylene glycol.

---
identifier: "/us/cfr/t21/s173.220"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 173.220 - 1,3-Butylene glycol."
title_number: 21
title_name: "Food and Drugs"
section_number: "173.220"
section_name: "1,3-Butylene glycol."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "B"
subchapter_name: "FOOD FOR HUMAN CONSUMPTION"
part_number: "173"
part_name: "SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 342, 348."
regulatory_source: "42 FR 14526, Mar. 15, 1977, unless otherwise noted."
cfr_part: "173"
---


# 173.220 1,3-Butylene glycol.

1,3-Butylene glycol (1,3-butanediol) may be safely used in food in accordance with the following prescribed conditions:

(a) The substance meets the following specifications:

(1) 1,3-Butylene glycol content: Not less than 99 percent.

(2) Specific gravity at 20/20 °C: 1.004 to 1.006.

(3) Distillation range: 200°-215 °C.

(b) It is used in the minimum amount required to perform its intended effect.

(c) It is used as a solvent for natural and synthetic flavoring substances except where standards of identity issued under section 401 of the act preclude such use.