21 CFR § 181.28 - Release agents.

---
identifier: "/us/cfr/t21/s181.28"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 181.28 - Release agents."
title_number: 21
title_name: "Food and Drugs"
section_number: "181.28"
section_name: "Release agents."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "B"
subchapter_name: "FOOD FOR HUMAN CONSUMPTION"
part_number: "181"
part_name: "PRIOR-SANCTIONED FOOD INGREDIENTS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 342, 348, 371."
regulatory_source: "42 FR 14638, Mar. 15, 1977, unless otherwise noted."
cfr_part: "181"
---


# 181.28 Release agents.

Substances classified as release agents, when migrating from food-packaging material shall include:

Dimethylpolysiloxane (substantially free from hydrolyzable chloride and alkoxy groups, no more than 18 percent loss in weight after heating 4 hours at 200 °C.; viscosity 300 centisokes, 600 centisokes at 25 °C, specific gravity 0.96 to 0.97 at 25 °C, refractive index 1.400 to 1.404 at 25 °C).

Linoleamide (linoleic acid amide).

Oleamide (oleic acid amide).

Palmitamide (palmitic acid amide).

Stearamide (stearic acid amide).

[42 FR 14638, Mar. 15, 1977; 42 FR 56728, Oct. 28, 1977]