21 CFR § 182.1180 - Caffeine.

---
identifier: "/us/cfr/t21/s182.1180"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 182.1180 - Caffeine."
title_number: 21
title_name: "Food and Drugs"
section_number: "182.1180"
section_name: "Caffeine."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "B"
subchapter_name: "FOOD FOR HUMAN CONSUMPTION"
part_number: "182"
part_name: "SUBSTANCES GENERALLY RECOGNIZED AS SAFE"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 342, 348, 371."
regulatory_source: "42 FR 14640, Mar. 15, 1977, unless otherwise noted."
cfr_part: "182"
---


# 182.1180 Caffeine.

(a) *Product.* Caffeine.

(b) *Tolerance.* 0.02 percent.

(c) *Limitations, restrictions, or explanation.* This substance is generally recognized as safe when used in cola-type beverages in accordance with good manufacturing practice.