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21 CFR § 182.1745 - Sodium carboxymethylcellulose.

---
identifier: "/us/cfr/t21/s182.1745"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 182.1745 - Sodium carboxymethylcellulose."
title_number: 21
title_name: "Food and Drugs"
section_number: "182.1745"
section_name: "Sodium carboxymethylcellulose."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "B"
subchapter_name: "FOOD FOR HUMAN CONSUMPTION"
part_number: "182"
part_name: "SUBSTANCES GENERALLY RECOGNIZED AS SAFE"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 342, 348, 371."
regulatory_source: "42 FR 14640, Mar. 15, 1977, unless otherwise noted."
cfr_part: "182"
---

# 182.1745 Sodium carboxymethylcellulose.

(a) *Product.* Sodium carboxymethylcellulose is the sodium salt of carboxymethylcellulose not less than 99.5 percent on a dry-weight basis, with maximum substitution of 0.95 carboxymethyl groups per anhydroglucose unit, and with a minimum viscosity of 25 centipoises for 2 percent by weight aqueous solution at 25 °C.

(b) *Conditions of use.* This substance is generally recognized as safe when used in accordance with good manufacturing practice.