21 CFR § 184.1563 - Ozone.

---
identifier: "/us/cfr/t21/s184.1563"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 184.1563 - Ozone."
title_number: 21
title_name: "Food and Drugs"
section_number: "184.1563"
section_name: "Ozone."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "B"
subchapter_name: "FOOD FOR HUMAN CONSUMPTION"
part_number: "184"
part_name: "DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 342, 348, 371."
regulatory_source: "42 FR 14653, Mar 15, 1977, unless otherwise noted."
cfr_part: "184"
---


# 184.1563 Ozone.

(a) Ozone (O<sub>3</sub>, CAS Reg. No. 10028-15-6) is an unstable blue gas with a pungent, characteristic odor, which occurs freely in nature, It is produced commercially by passing electrical discharges or ionizing radiation through air or oxygen.

(b) The ingredient must be of a purity suitable for its intended use in accordance with § 170.30(h)(1) of this chapter.

(c) In accordance with § 184.1(b)(2), the ingredient is used to treat food only within the following specific limitations:

| Category of food | Maximum treatment level in food | Functional use |
| --- | --- | --- |
| Bottled water that prior to ozonation meets the microbiological, physical, chemical, and radiological quality standards of § 165.110 (b)(2) through (b)(5) of this chapter | Not to exceed current good manufacturing practice. Current good manufacturing practice results in a maximum residual level at the time of bottling of 0.4 milligram of ozone per liter of bottled water | Antimicrobial agent, § 170.3 (o)(2) of this chapter. |

[47 FR 50210, Nov. 5, 1982, as amended at 60 FR 57130, Nov. 13, 1995]