21 CFR § 358.720 - Permitted combinations of active ingredients.

---
identifier: "/us/cfr/t21/s358.720"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 358.720 - Permitted combinations of active ingredients."
title_number: 21
title_name: "Food and Drugs"
section_number: "358.720"
section_name: "Permitted combinations of active ingredients."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "D"
subchapter_name: "DRUGS FOR HUMAN USE"
part_number: "358"
part_name: "MISCELLANEOUS EXTERNAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 351, 352, 353, 355, 360, 371."
regulatory_source: "55 FR 33255, Aug. 14, 1990, unless otherwise noted."
cfr_part: "358"
---


# 358.720 Permitted combinations of active ingredients.

(a) *Combination of active ingredients for the control of dandruff.* Salicylic acid identified in § 358.710(a)(4) may be combined with sulfur identified in § 358.710(a)(7) provided each ingredient is present within the established concentration and the product is labeled according to § 358.750.

(b) *Combination of control of dandruff and external analgesic active ingredients.* Coal tar identified in § 358.710(a)(1) may be used at a concentration of 1.8 percent coal tar solution, on a weight to volume basis, in combination with menthol, 1.5 percent, in a shampoo formulation provided the product is labeled according to § 358.760.

[72 FR 9852, Mar. 6, 2007]