21 CFR § 520.110 - Apramycin sulfate soluble powder.

---
identifier: "/us/cfr/t21/s520.110"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 520.110 - Apramycin sulfate soluble powder."
title_number: 21
title_name: "Food and Drugs"
section_number: "520.110"
section_name: "Apramycin sulfate soluble powder."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "520"
part_name: "ORAL DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13838, Mar. 27, 1975, unless otherwise noted."
cfr_part: "520"
---


# 520.110 Apramycin sulfate soluble powder.

(a) *Specifications.* A water soluble powder used to make a medicated drinking water containing apramycin sulfate equivalent to 0.375 gram of apramycin activity per gallon of drinking water.

(b) *Sponsor.* See No. 058198 in § 510.600(c) of this chapter.

(c) *Related tolerances.* See § 556.52 of this chapter.

(d) *Conditions of use in swine*—(1) *Amount.* Administer in drinking water at the rate of 12.5 milligrams of apramycin per kilogram (5.7 milligrams per pound) of body weight per day for 7 days.

(2) *Indications for use.* For the control of porcine colibacillosis (weanling pig scours) caused by strains of *Escherichia coli* sensitive to apramycin.

(3) *Limitations.* Do not slaughter treated swine for 28 days following treatment. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[47 FR 15771, Apr. 13, 1982, as amended at 49 FR 19642, May 9, 1984; 53 FR 37753, Sept. 28, 1988; 79 FR 28818, May 20, 2014; 81 FR 48702, July 26, 2016; 81 FR 94989, Dec. 27, 2016]