21 CFR § 520.1408 - Methylprednisolone.

---
identifier: "/us/cfr/t21/s520.1408"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 520.1408 - Methylprednisolone."
title_number: 21
title_name: "Food and Drugs"
section_number: "520.1408"
section_name: "Methylprednisolone."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "520"
part_name: "ORAL DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13838, Mar. 27, 1975, unless otherwise noted."
cfr_part: "520"
---


# 520.1408 Methylprednisolone.

(a) *Specifications.* Each tablet contains 1, 2, or 4 milligrams (mg) of methylprednisolone.

(b) *Sponsors.* See Nos. 054771 and 069043 in § 510.600(c) of this chapter.

(c) *Conditions of use in dogs and cats*—(1) *Amount.* 5 to 15 pounds (lbs): 2 mg; 15 to 40 lbs: 2 to 4 mg; 40 to 80 lbs: 4 to 8 mg. Administer total daily dose orally in equally divided doses 6 to 10 hours apart until response is noted or 7 days have elapsed.

(2) *Indications for use.* As an anti-inflammatory agent.

(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[78 FR 28824, May 20, 2014, as amended at 83 FR 48946, Sept. 28, 2018; 89 FR 14410, Feb. 27, 2024]