21 CFR § 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets.

---
identifier: "/us/cfr/t21/s520.1872"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 520.1872 - Praziquantel, pyrantel pamoate, and febantel tablets."
title_number: 21
title_name: "Food and Drugs"
section_number: "520.1872"
section_name: "Praziquantel, pyrantel pamoate, and febantel tablets."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "520"
part_name: "ORAL DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13838, Mar. 27, 1975, unless otherwise noted."
cfr_part: "520"
---


# 520.1872 Praziquantel, pyrantel pamoate, and febantel tablets.

(a) *Specifications.* Each tablet or chewable tablet contains either:

(1) Tablet No. 1: 22.7 milligrams praziquantel, 22.7 milligrams pyrantel base, and 113.4 milligrams febantel; or

(2) Tablet No. 2: 68 milligrams praziquantel, 68 milligrams pyrantel base, and 340.2 milligrams febantel.

(3) Tablet No. 3: 136 milligrams (mg) praziquantel, 136 mg pyrantel base, and 680.4 mg febantel.

(b) *Sponsor.* See No. 058198 in § 510.600(c) of this chapter.

(c) *Conditions of use*—(1) *Dogs*—(i) *Amount.* Administer as a single dose directly by mouth or in a small amount of food as follows:

| Kilograms | Pounds | Tablet no. 1 | Tablet no. 2 | Tablet no. 3 |
| --- | --- | --- | --- | --- |
| 0.9 to 1.8 | 2 to 4 | 1/2 |  |  |
| 2.3 to 3.2 | 5 to 7 | 1 |  |  |
| 3.6 to 5.4 | 8 to 12 | 1 1/2 |  |  |
| 5.9 to 8.2 | 13 to 18 | 2 |  |  |
| 8.6 to 11.4 | 19 to 25 | 2 1/2 |  |  |
| 11.8 to 13.6 | 26 to 30 |  | 1 |  |
| 14.1 to 20.0 | 31 to 44 |  | 1 1/2 |  |
| 20.4 to 27.2 | 45 to 60 |  | 2 | 1 |
| 27.7 to 40.9 | 61 to 90 |  |  | 1 1/2 |
| 41.3 to 54.5 | 91 to 120 |  |  | 2 |

(ii) *Indications for use.* For the removal of tapeworms (*Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus*); hookworms (*Ancylostoma caninum, Uncinaria stenocephala*); ascarids (*Toxocara canis, Toxascaris leonina*); and whipworms (*Trichuris vulpis*) and for the removal and control of tapeworm *Echinococcus multilocularis* in dogs.

(iii) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.

(2) [Reserved]

[59 FR 33908, July 1, 1994, as amended at 61 FR 29651, June 12, 1996; 68 FR 22293, Apr. 28, 2003; 71 FR 6677, Feb. 9, 2006; 86 FR 14819, Mar. 19, 2021; 87 FR 58961, Sept. 29, 2022]