21 CFR § 520.2345e - Tetracycline solution.

---
identifier: "/us/cfr/t21/s520.2345e"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 520.2345e - Tetracycline solution."
title_number: 21
title_name: "Food and Drugs"
section_number: "520.2345e"
section_name: "Tetracycline solution."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "520"
part_name: "ORAL DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13838, Mar. 27, 1975, unless otherwise noted."
cfr_part: "520"
---


# 520.2345e Tetracycline solution.

(a) *Specifications.* Each milliliter contains the equivalent of either 25 or 100 milligrams of tetracycline hydrochloride.

(b) *Sponsor.* See No. 054771 in § 510.600(c) of this chapter.

(c) *Conditions of use*—(1) *Dogs*—(i) *Amount.* 25 milligrams per pound of body weight per day in divided doses every 6 hours.

(ii) *Indications for use.* Treatment of infections caused by organisms sensitive to tetracycline hydrochloride, such as bacterial gastroenteritis due to *Escherichia coli* and urinary tract infections due to *Staphylococcus* spp. and *E. coli.*

(iii) *Limitations.* Administer orally; continue treatment until symptoms have subsided and the temperature is normal for 48 hours; not for use in animals which are raised for food production; Federal law restricts this drug to use by or on the order of a licensed veterinarian.

(2) *Dogs and cats*—(i) *Amount.* 25 milligrams per pound of body weight per day in divided doses every 6 hours.

(ii) *Indications for use.* Treatment of infections caused by organisms susceptible to tetracycline hydrochloride, such as bacterial gastroenteritis due to *E. coli* and urinary tract infections due to *Staphylococcus* spp. and *E. coli.*

(iii) *Limitations.* Administer orally; continue treatment until the temperature has been normal for 48 hours; not for use in food-producing animals; Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[57 FR 37329, Aug. 18, 1992, as amended at 79 FR 28831, May 20, 2014]