21 CFR § 522.1223 - Ketamine, promazine, and aminopentamide.

---
identifier: "/us/cfr/t21/s522.1223"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 522.1223 - Ketamine, promazine, and aminopentamide."
title_number: 21
title_name: "Food and Drugs"
section_number: "522.1223"
section_name: "Ketamine, promazine, and aminopentamide."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "522"
part_name: "IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13858, Mar. 27, 1975, unless otherwise noted."
cfr_part: "522"
---


# 522.1223 Ketamine, promazine, and aminopentamide.

(a) *Specifications.* Each milliliter of solution contains ketamine hydrochloride equivalent to 100 milligrams (mg) ketamine base activity, 7.5 (mg) of promazine hydrochloride, and 0.0625 mg of aminopentamide hydrogen sulfate.

(b) *Sponsor.* See No. 054771 in § 510.600(c) of this chapter.

(c) *Conditions of use in cats*—(1) *Amount.* Administer by intramuscular injection 15 to 20 mg ketamine base per pound of body weight, depending on the effect desired.

(2) *Indications for use.* It is used in cats as the sole anesthetic agent for ovariohysterectomy and general surgery.

(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[79 FR 16191, Mar. 25, 2014]