21 CFR § 522.1372 - Mepivacaine.

---
identifier: "/us/cfr/t21/s522.1372"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 522.1372 - Mepivacaine."
title_number: 21
title_name: "Food and Drugs"
section_number: "522.1372"
section_name: "Mepivacaine."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "522"
part_name: "IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13858, Mar. 27, 1975, unless otherwise noted."
cfr_part: "522"
---


# 522.1372 Mepivacaine.

(a) *Specifications.* Each milliliter (mL) of solution contains 20 milligrams mepivacaine hydrochloride.

(b) *Sponsor.* See No. 054771 in § 510.600(c) of this chapter.

(c) *Conditions of use in horses*—(1) *Amount.* For nerve block, 3 to 15 mL; for epidural anesthesia, 5 to 20 mL; for intra-articular anesthesia, 10 to 15 mL; for infiltration, as required; for anesthesia of the laryngeal mucosa prior to ventriculectomy, by topical spray, 25 to 40 mL, by infiltration, 20 to 50 mL.

(2) *Indications for use.* For use as a local anesthetic for infiltration, nerve block, intra-articular and epidural anesthesia, and topical and/or infiltration anesthesia of the laryngeal mucosa prior to ventriculectomy.

(3) *Limitations.* Not for use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[71 FR 39547, July 13, 2006, as amended at 79 FR 16191, Mar. 25, 2014; 88 FR 14898, Mar. 10, 2023]