21 CFR § 522.1452 - Nalorphine.

---
identifier: "/us/cfr/t21/s522.1452"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 522.1452 - Nalorphine."
title_number: 21
title_name: "Food and Drugs"
section_number: "522.1452"
section_name: "Nalorphine."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "522"
part_name: "IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13858, Mar. 27, 1975, unless otherwise noted."
cfr_part: "522"
---


# 522.1452 Nalorphine.

(a) *Specifications.* Each milliliter of solution contains 5 milligrams of nalorphine hydrochloride.

(b) *Sponsor.* See No. 000010 in § 510.600(c) of this chapter.

(c) *Conditions of use in dogs*—(1) *Amount.* One milligram per 5 pounds; intravenously, intramuscularly, or subcutaneously.

(2) *Indications for use.* Respiratory and circulatory depression in dogs resulting from overdosage of, or unusual sensitivity to, morphine and certain other narcotics. Not for depression due to any other cause.

(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[44 FR 6707, Feb. 2, 1979, as amended at 47 FR 36418, Aug. 20, 1982; 62 FR 63271, Nov. 28, 1997; 79 FR 16191, Mar. 25, 2014; 84 FR 39184, Aug. 9, 2019]