21 CFR § 522.1920 - Prochlorperazine and isopropamide.

---
identifier: "/us/cfr/t21/s522.1920"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 522.1920 - Prochlorperazine and isopropamide."
title_number: 21
title_name: "Food and Drugs"
section_number: "522.1920"
section_name: "Prochlorperazine and isopropamide."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "522"
part_name: "IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13858, Mar. 27, 1975, unless otherwise noted."
cfr_part: "522"
---


# 522.1920 Prochlorperazine and isopropamide.

(a) *Specifications.* Each milliliter of solution contains prochlorperazine edisylate equivalent to 4 milligrams (mg) prochlorperazine and isopropamide iodide equivalent to 0.28 mg of isopropamide.

(b) *Sponsor.* See No. 054771 in § 510.600(c) of this chapter.

(c) *Conditions of use*—(1) *Amount.* (i) Dosage is administered by subcutaneous injection twice daily as follows:

| Weight of animal in pounds | Dosage inmilliliters |
| --- | --- |
| Up to 4 | 0.25 |
| 5 to 14 | 0.5-1 |
| 15 to 30 | 2-3 |
| 30 to 45 | 3-4 |
| 45 to 60 | 4-5 |
| Over 60 | 6 |

(ii) Following the last injection, administer prochlorperazine and isopropamide sustained release capsules as indicated.

(2) *Indications for use.* For use in dogs and cats in which gastrointestinal disturbances are associated with emotional stress.

(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[79 FR 16194, Mar. 25, 2014]