21 CFR § 522.2424 - Thiamylal.

---
identifier: "/us/cfr/t21/s522.2424"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 522.2424 - Thiamylal."
title_number: 21
title_name: "Food and Drugs"
section_number: "522.2424"
section_name: "Thiamylal."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "522"
part_name: "IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13858, Mar. 27, 1975, unless otherwise noted."
cfr_part: "522"
---


# 522.2424 Thiamylal.

(a) *Specifications.* The drug is a sterile powder. It is reconstituted with sterile distilled water, water for injection, or sodium chloride injection, to a desired concentration of 0.5 to 4 percent sodium thiamylal.

(b) *Sponsors.* See Nos. 054771 and 069043 in § 510.600(c) of this chapter.

(c) *Conditions of use*—(1) *Amount.* Administer by intravenous injection to effect. The average single dose is:

(i) *Dogs and cats:* 8 milligrams (mg) per pound of body weight (when used with a preanesthetic, generally one-half the normal dose).

(ii) *Swine:* 40 mg per 5 pounds (lbs) of body weight.

(iii) *Horses:* Light anesthesia, 1 gram per 500 lbs to 1,100 lbs of body weight; deep anethesia, 1 gram per 300 lbs of body weight (40 mg/12 lbs of body weight).

(iv) *Cattle:* Short duration, 20 mg/5 lbs of body weight; longer duration, 40 mg/7 lbs of body weight.

(2) *Indications for use.* It is used as an ultra-short-acting anesthetic in dogs, cats, swine, horses, and cattle.

(3) *Limitations.* Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[79 FR 16196, Mar. 25, 2014, as amended at 83 FR 48946, Sept. 28, 2018]