21 CFR § 522.390 - Chloramphenicol.

---
identifier: "/us/cfr/t21/s522.390"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 522.390 - Chloramphenicol."
title_number: 21
title_name: "Food and Drugs"
section_number: "522.390"
section_name: "Chloramphenicol."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "522"
part_name: "IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13858, Mar. 27, 1975, unless otherwise noted."
cfr_part: "522"
---


# 522.390 Chloramphenicol.

(a) *Specifications.* Each milliliter of solution contains 100 milligrams of chloramphenicol.

(b) *Sponsor.* See Nos. 054771 and 069043 in § 510.600(c) of this chapter.

(c) *Conditions of use.* *Dogs*—(1) *Amount.* 5 to 15 milligrams per pound of body weight, intramuscularly or intravenously, every 6 hours. In severe infections, use 4 to 6 hour treatment intervals the first day. If no response is obtained in 3 to 5 days, discontinue use and reevaluate diagnosis.

(2) *Indications for use.* Treatment of infections of the respiratory tract, the urinary tract, and enteritis and tonsillitis caused by organisms susceptible to chloramphenicol.

(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian. Federal law prohibits the extralabel use of this drug in food-producing animals.

[57 FR 37331, Aug. 18, 1992, as amended at 65 FR 45877, July 26, 2000; 78 FR 17597, Mar. 22, 2013; 79 FR 16185, Mar. 25, 2014; 81 FR 17608, Mar. 30, 2016]