21 CFR § 524.1484e - Neomycin and polymyxin B ophthalmic solution.
---
identifier: "/us/cfr/t21/s524.1484e"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 524.1484e - Neomycin and polymyxin B ophthalmic solution."
title_number: 21
title_name: "Food and Drugs"
section_number: "524.1484e"
section_name: "Neomycin and polymyxin B ophthalmic solution."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "524"
part_name: "OPHTHALMIC AND TOPICAL DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13873, Mar. 27, 1975, unless otherwise noted."
cfr_part: "524"
---
# 524.1484e Neomycin and polymyxin B ophthalmic solution.
(a) *Specifications.* Each milliliter of the ophthalmic preparation contains 5.0 milligrams neomycin sulfate (3.5 milligrams neomycin base), and 10,000 Units of polymyxin B sulfate.
(b) *Sponsor.* See No. 054771 in § 510.600(c) of this chapter.
(c) *Conditions of use in dogs*—(1) *Amount.* Instill 1 to 2 drops per eye every 6 hours.
(2) *Indications for use.* For the treatment of bacterial infections associated with topical ophthalmological conditions such as corneal injuries, superficial keratitis, conjunctivitis, keratoconjunctivitis, and blepharitis.
(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.
[40 FR 13873, Mar. 27, 1975, as amended at 61 FR 5507, Feb. 13, 1996; 79 FR 10970, Feb. 27, 2014]