21 CFR § 524.815 - Eprinomectin and praziquantel.

---
identifier: "/us/cfr/t21/s524.815"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 524.815 - Eprinomectin and praziquantel."
title_number: 21
title_name: "Food and Drugs"
section_number: "524.815"
section_name: "Eprinomectin and praziquantel."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "524"
part_name: "OPHTHALMIC AND TOPICAL DOSAGE FORM NEW ANIMAL DRUGS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 360b."
regulatory_source: "40 FR 13873, Mar. 27, 1975, unless otherwise noted."
cfr_part: "524"
---


# 524.815 Eprinomectin and praziquantel.

(a) *Specifications.* Each milliliter (mL) of solution contains 4 milligrams (mg) eprinomectin and 83 mg praziquantel.

(b) *Sponsor.* See No. 000010 in § 510.600(c) of this chapter.

(c) *Conditions of use in cats*—(1) *Amount.* Using the 0.3 mL and 0.9 mL unit applicators, administer a minimum dose of 0.23 mg eprinomectin per pound body weight and 4.55 mg praziquantel per pound body weight by topical application on the dorsal midline between the base of the skull and the shoulder blades.

(2) *Indications for use.* For the prevention of heartworm disease caused by *Dirofilaria immitis,* and for the treatment and control of roundworms (adult and fourth stage larval *Toxocara cati*), hookworms (adult and fourth stage larval *Ancylostoma tubaeforme;* adult *Ancylostoma braziliense*), and tapeworms (adult *Dipylidium caninum* and *Echinococcus multilocularis*), in cats and kittens 7 weeks of age and older and 1.8 lbs or greater.

(3) *Limitations.* Federal law restricts this drug to use by or on the order of a licensed veterinarian.

[83 FR 48946, Sept. 28, 2018, as amended at 84 FR 39184, Aug. 9, 2019]