21 CFR § 558.175 - Clopidol.

---
identifier: "/us/cfr/t21/s558.175"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 558.175 - Clopidol."
title_number: 21
title_name: "Food and Drugs"
section_number: "558.175"
section_name: "Clopidol."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "558"
part_name: "NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 354, 360b, 360ccc, 360ccc-1, 371."
regulatory_source: "40 FR 13959, Mar. 27, 1975, unless otherwise noted."
cfr_part: "558"
---


# 558.175 Clopidol.

(a) *Specifications.* Type A medicated article containing 25 percent clopidol.

(b) *Sponsor.* See No. 016592 in § 510.600(c) of this chapter.

(c) *Related tolerances.* See § 556.160 of this chapter.

(d) *Conditions of use*—(1) *Chickens*—

| Clopidol ingrams per ton | Combination in grams per ton | Indications for use | Limitations | Sponsors |
| --- | --- | --- | --- | --- |
| (i) 113.5 |  | Broiler chickens and re-placement chickens intended for use as caged layers: As an aid in the prevention of coccidiosis caused by  and | Do not feed to chickens over 16 weeks of age | 016592 |
| (ii) 113.5 | Bacitracin methylenedisalicylate, 4 to 50 | Broiler chickens: As an aid in the prevention of coccidiosis caused by  and  and for increased rate of weight gain. | Feed continuously as the sole ration from the time chicks are placed in floor pens until slaughter. Do not feed to chickens over 16 weeks of age; bacitracin methylenedisalicylate as provided by No. 054771 in § 510.600(c) of this chapter | 016592 |
| (iii) 113.5 | Bacitracin zinc, 5 to 25 | Broiler chickens: As an aid in the prevention of coccidiosis caused by  and  and for increased rate of weight gain and improved feed efficiency. | Feed continuously as sole ration; bacitracin zinc as provided by No. 054771 in § 510.600(c) of this chapter | 054771 016592 |
| (iv) 113.5 | Bambermycins, 1 to 2 | Broiler chickens: As an aid in prevention of coccidiosis caused by  and  and for increased rate of weight gain and improved feed efficiency. | Feed continuously as the sole ration. Do not feed to chickens over 16 weeks of age | 016592 |
| (v) 227 |  | Broiler and replacement chickens intended for use as caged layers: As an aid in the prevention of coccidiosis caused by  and | Feed continuously as the sole ration; feed up to 16 weeks of age if intended for use as caged layers; withdraw 5 days before slaughter if given at the level of 0.025 percent in feed or reduce level to 0.0125 percent 5 days before slaughter | 016592 |
| (vi) 227 | Bambermycins, 1 to 2 | Broiler chickens: As an aid in prevention of coccidiosis caused by  and  and for increased rate of weight gain and improved feed efficiency. | Feed continuously as sole ration until 5 days before slaughter. Withdraw 5 days before slaughter or feed 113.5 g/ton clopidol and 1 to 2 g/ton bambermycins during those 5 days before slaughter. Do not feed to chickens over 16 weeks of age | 016592 |

(2) *Turkeys*—

| Clopidol ingrams per ton | Combination in grams per ton | Indications for use | Limitations | Sponsors |
| --- | --- | --- | --- | --- |
| (i) 113.5 or 227 |  | Turkeys: As an aid in the prevention of leucocytozoonosis caused by | For turkeys grown for meat purposes only; feed continuously as the sole ration at 0.0125 or 0.025 percent clopidol depending on management practices, degree of exposure, and amount of feed eaten; withdraw 5 days before slaughter | 016592 |
| (ii) [Reserved] |  |  |  |  |

(3) *Combinations.* Clopidol may also be used in combination with:

(i) Chlortetracycline as in § 558.128.

(ii) Lincomycin as in § 558.325.

[68 FR 17882, Apr. 14, 2003, as amended at 72 FR 60551, Oct. 25, 2007; 74 FR 61028, Nov. 23, 2009; 79 FR 10965, 10982, Feb. 27, 2014; 79 FR 13545, Mar. 11, 2014; 81 FR 17609, Mar. 30, 2016; 81 FR 95004, Dec. 27, 2016; 84 FR 12495, Apr. 2, 2019; 86 FR 14822, Mar. 19, 2021]