21 CFR § 573.225 - 1,3-Butylene glycol.

---
identifier: "/us/cfr/t21/s573.225"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 573.225 - 1,3-Butylene glycol."
title_number: 21
title_name: "Food and Drugs"
section_number: "573.225"
section_name: "1,3-Butylene glycol."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "573"
part_name: "FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 342, 348."
regulatory_source: "41 FR 38652, Sept. 10, 1976, unless otherwise noted."
cfr_part: "573"
---


# 573.225 1,3-Butylene glycol.

The food additive 1,3-butylene glycol (1,3-butanediol) may be safely used in accordance with the following prescribed conditions:

(a) It complies with the specifications in § 173.220(a) of this chapter.

(b) It is intended for use in swine feed as a source of energy.

(c) It is to be thoroughly mixed into feed at levels not to exceed 9 percent of the dry matter of the total ration.

(d) 1,3-Butylene glycol should be mixed in feed with equipment adapted for the addition of liquids, and the feed should be mixed not less than 5 minutes after its addition.

[53 FR 40061, Oct. 13, 1988]