40 CFR § 174.27 - Active ingredient of a loss-of-function plant-incorporated protectant.

---
identifier: "/us/cfr/t40/s174.27"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "40 CFR § 174.27 - Active ingredient of a loss-of-function plant-incorporated protectant."
title_number: 40
title_name: "Protection of Environment"
section_number: "174.27"
section_name: "Active ingredient of a loss-of-function plant-incorporated protectant."
chapter_name: "ENVIRONMENTAL PROTECTION AGENCY"
subchapter_number: "E"
subchapter_name: "PESTICIDE PROGRAMS"
part_number: "174"
part_name: "PROCEDURES AND REQUIREMENTS FOR PLANT-INCORPORATED PROTECTANTS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "7 U.S.C. 136-136y; 21 U.S.C. 321(q), 346a and 371."
regulatory_source: "66 FR 37814, July 19, 2001, unless otherwise noted."
cfr_part: "174"
---


# 174.27 Active ingredient of a loss-of-function plant-incorporated protectant.

The active ingredient is exempt if the following conditions are met:

(a) The genetic material of a native gene is modified using genetic engineering to result in a pesticidal effect through the reduction or elimination of the activity of that gene; and

(b) This exemption does not apply until the requirements in § 174.21(d) have been met.

[88 FR 34777, May 31, 2023]