# 180.700 Afidopyropen; tolerances for residues.
(a) *General.* (1) Tolerances are established for residues of afidopyropen, including its metabolites and degradates, in or on the commodities in table 1 to this paragraph (a)(1). Compliance with the tolerance levels specified in this paragraph (a)(1) is to be determined by measuring only afidopyropen, [(3*S,*4*R,*4a*R,*6*S,*6a*S,*12*R,*12a*S,*12b*S*)-3-[(cyclopropylcarbonyl)oxy]-1,3,4,4a,5,6a,12,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridinyl)2*H,*11*H*-naphtho[2,1-*b*]pyrano[3,4-*e*]pyran-4-yl]methyl cyclopropanecarboxylate, in or on the following food commodities:
Table 1 to Paragraph **(a)**(1)
| Commodity | Parts permillion |
| --- | --- |
| Alfalfa, seed | 0.3 |
| Almond, hulls | 0.3 |
| Animal feed, nongrass, group 18, forage | 4 |
| Animal feed, nongrass, group 18, hay | 9 |
| Animal feed, nongrass, group 18, straw | 5 |
| Apple, wet pomace | 0.05 |
| Brassica, head and stem, group 5-16 | 0.50 |
| Brassica, leafy greens, subgroup 4-16B | 5.0 |
| Citrus, oil | 0.40 |
| Cotton, gin byproducts | 2.0 |
| Cotton, undelinted seed | 0.08 |
| Fruit, citrus, group 10-10 | 0.15 |
| Fruit, pome, group 11-10 | 0.02 |
| Fruit, stone, group 12-12 | 0.03 |
| Grain, aspirated fractions | 60 |
| Grass, forage, fodder and hay, group 17 | 10 |
| Leafy Greens, subgroup 4-16A | 2.0 |
| Leaf petiole vegetable subgroup 22B | 3.0 |
| Lettuce, leaf | 7 |
| Nut, tree, group 14-12 | 0.01 |
| Sorghum, grain, forage | 0.3 |
| Sorghum, grain, grain | 0.15 |
| Sorghum, grain, stover | 0.3 |
| Sorghum, sweet, forage | 0.3 |
| Sorghum, sweet, grain | 0.15 |
| Sorghum, sweet, stalk | 0.3 |
| Sorghum, sweet, stover | 0.3 |
| Soybean, forage | 0.15 |
| Soybean, hay | 0.4 |
| Soybean, seed | 0.01 |
| Strawberry | 0.3 |
| Tomato, dried | 0.50 |
| Vegetable, cucurbit, group 9 | 0.70 |
| Vegetable, fruiting, group 8-10 | 0.2 |
| Vegetable, tuberous and corm, subgroup 1C | 0.01 |
(2) Tolerances are established for residues of afidopyropen, including its metabolites and degradates, in or on the commodities in table 2 to this paragraph (a)(2). Compliance with the tolerance levels specified in this paragraph (a)(2) is to be determined by measuring only the sum of afidopyropen, [(3*S,*4*R,*4a*R,*6*S,*6a*S,*12*R,*12a*S,*12b*S*)-3-[(cyclopropylcarbonyl)oxy]-1,3,4,4a,5,6a,12,12a,12b-decahydro-6,12-dihydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridinyl)2*H,*11*H*-naphtho[2,1-*b*]pyrano[3,4-*e*]pyran-4-yl]methyl cyclopropanecarboxylate and its metabolite cyclopropanecarboxylic acid carnitine (CPCA-carnitine), calculated as the stoichiometric equivalent of afidopyropen in or on the following animal commodities:
Table 2 to Paragraph **(a)**(2)
| Commodity | Parts per million |
| --- | --- |
| Cattle, meat | 0.2 |
| Cattle, meat byproducts | 0.2 |
| Goat, meat | 0.2 |
| Goat, meat byproducts | 0.2 |
| Horse, meat | 0.2 |
| Horse, meat byproducts | 0.2 |
| Milk | 0.04 |
| Sheep, meat | 0.2 |
| Sheep, meat byproducts | 0.2 |
(b) [Reserved]
(c) *Tolerances with regional registrations.* [Reserved]
(d) *Indirect or inadvertent residues.* [Reserved]
[83 FR 46401, Sept. 13, 2018, as amended at 85 FR 63459, Oct. 8, 2020; 89 FR 51848, June 20, 2024; 90 FR 34608, July 23, 2025; 91 FR 6789, Feb. 13, 2026]