# 721.12043 Heptane, 2-methoxy-2-methyl-.
(a) *Chemical substance and significant new uses subject to reporting.* (1) The chemical substance identified as heptane, 2-methoxy-2-methyl- (PMN P-18-127; CASRN 76589-16-7) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i) *Protection in the workplace.* Requirements as specified in § 721.63(a)(1) and (3), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (*e.g.,* enclosure or confinement of the operation, general and local ventilation) or administrative control measures (*e.g.,* workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible.
(ii) *Hazard communication.* Requirements as specified in § 721.72(a) through (d), (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(g)(1), this substance may cause: skin sensitization and specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
(iii) *Industrial, commercial, and consumer activities.* Requirements as specified in § 721.80(f). It is a significant new use to manufacture the substance unless by import into the United States in a solution of no greater than 5% by weight (*i.e.,* no domestic manufacture). It is a significant new use to process the substance unless in a solution of no greater than 5% by weight of the substance. It is a significant new use to process for use or use the substance in consumer products unless the concentration of the substance is less than 1% by weight.
(iv) *Release to water.* Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=210.
(b) *Specific requirements.* The provisions of Subpart A of this part apply to this section except as modified by this paragraph (b).
(1) *Recordkeeping.* Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance.
(2) *Limitation or revocation of certain notification requirements.* The provisions of § 721.185 apply to this section.
[90 FR 33287, July 17, 2025]