40 CFR § 721.12050 - 1,5-Pentanediamine, 2-methyl-, hydrochloride (1:2).

---
identifier: "/us/cfr/t40/s721.12050"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "40 CFR § 721.12050 - 1,5-Pentanediamine, 2-methyl-, hydrochloride (1:2)."
title_number: 40
title_name: "Protection of Environment"
section_number: "721.12050"
section_name: "1,5-Pentanediamine, 2-methyl-, hydrochloride (1:2)."
chapter_name: "ENVIRONMENTAL PROTECTION AGENCY"
subchapter_number: "R"
subchapter_name: "TOXIC SUBSTANCES CONTROL ACT"
part_number: "721"
part_name: "SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES"
positive_law: false
currency: "2026-03-24"
last_updated: "2026-03-24"
format_version: "1.1.0"
generator: "[email protected]"
authority: "15 U.S.C. 2604, 2607, and 2625(c)."
regulatory_source: "49 FR 35018, Sept. 5, 1984, unless otherwise noted."
cfr_part: "721"
---


# 721.12050 1,5-Pentanediamine, 2-methyl-, hydrochloride (1:2).

(a) *Chemical substance and significant new uses subject to reporting.* (1) The chemical substance identified as 1,5-pentanediamine, 2-methyl-, hydrochloride (1:2) (PMN P-22-3; CASRN 34813-63-3) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.

(2) The significant new uses are:

(i) *Protection in the workplace.* Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (*e.g.,* enclosure or confinement of the operation, general and local ventilation) or administrative control measures (*e.g.,* workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 1.0%.

(ii) *Hazard communication.* Requirements as specified in § 721.72(a) through (f), (g)(1), (g)(3)(iii), and (g)(5). For purposes of § 721.72(e), the concentration is set at 1.0%. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity, skin irritation, and eye irritation. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.

(iii) *Industrial, commercial, and consumer activities.* Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure to the substance.

(iv) *Release to water.* Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=570 in aggregate of P-22-3, P-22-4, P-22-5, and P-22-6.

(b) *Specific requirements.* The provisions of Subpart A of this part apply to this section except as modified by this paragraph (b).

(1) *Recordkeeping.* Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance.

(2) *Limitation or revocation of certain notification requirements.* The provisions of § 721.185 apply to this section.

[90 FR 33287, July 17, 2025]