40 CFR § 725.1081 - Trichoderma reesei modified (generic).

---
identifier: "/us/cfr/t40/s725.1081"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "40 CFR § 725.1081 - Trichoderma reesei modified (generic)."
title_number: 40
title_name: "Protection of Environment"
section_number: "725.1081"
section_name: "Trichoderma reesei modified (generic)."
chapter_name: "ENVIRONMENTAL PROTECTION AGENCY"
subchapter_number: "R"
subchapter_name: "TOXIC SUBSTANCES CONTROL ACT"
part_number: "725"
part_name: "REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS"
positive_law: false
currency: "2026-03-24"
last_updated: "2026-03-24"
format_version: "1.1.0"
generator: "[email protected]"
authority: "15 U.S.C. 2604, 2607, 2613, and 2625."
regulatory_source: "62 FR 17932, Apr. 11, 1997, unless otherwise noted."
cfr_part: "725"
---


# 725.1081 Trichoderma reesei modified (generic).

(a) *Microorganism and significant new uses subject to reporting.* (1) The genetically modified microorganism generically identified as *Trichoderma reesei* modified (MCAN J-16-26) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.

(2)(i) It is a significant new use to manufacture, process, or use the microorganism other than in a fermentation system that meets all of the following conditions:

(A) Enzyme production occurs by submerged fermentation (*i.e.,* for enzyme production, growth of the microorganism occurs beneath the surface of the liquid growth medium); and

(B) Any fermentation of solid plant material or insoluble substrate to which *Trichoderma reesei* fermentation broth is added after the standard industrial fermentation is completed is initiated only after the inactivation of the microorganism as delineated in § 725.422(d).

(ii) [Reserved]

(b) *Specific requirements.* The provisions of subpart L of this part apply to this section except as modified by this paragraph (b).

(1) *Recordkeeping.* Recordkeeping requirements as specified in § 725.950(b)(2) through (4) are applicable to manufacturers and processors of this microorganism.

(2) *Modification or revocation of certain notification requirements.* The provisions of § 725.984 apply to this section.

[87 FR 73955, Dec. 2, 2022]