40 CFR § 725.50 - EPA Review.

---
identifier: "/us/cfr/t40/s725.50"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "40 CFR § 725.50 - EPA review."
title_number: 40
title_name: "Protection of Environment"
section_number: "725.50"
section_name: "EPA review."
chapter_name: "ENVIRONMENTAL PROTECTION AGENCY"
subchapter_number: "R"
subchapter_name: "TOXIC SUBSTANCES CONTROL ACT"
part_number: "725"
part_name: "REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "15 U.S.C. 2604, 2607, 2613, and 2625."
regulatory_source: "62 FR 17932, Apr. 11, 1997, unless otherwise noted."
cfr_part: "725"
---


# 725.50 EPA review.

(a) *MCANs.* The review period specified in section 5(a) of the Act for MCANs runs for 90 days from the date the Document Control Officer receives a complete submission, or the date EPA determines the submission is complete under § 725.33, unless the Agency extends the review period under section 5(c) of the Act and § 725.56.

(b) *Exemption requests.* The review period starts on the date the Document Control Officer receives a complete exemption request, or the date EPA determines the request is complete under § 725.33, unless the Agency extends the review period under § 725.56. The review periods for exemption requests run as follows:

(1) *TERAs.* The review period for TERAs is 60 days.

(2) *TMEs.* The review period for TMEs is 45 days.

(3) *Tier II exemption requests.* The review period for Tier II exemption requests is 45 days.