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40 CFR § 761.395 - A validation study.

---
identifier: "/us/cfr/t40/s761.395"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "40 CFR § 761.395 - A validation study."
title_number: 40
title_name: "Protection of Environment"
section_number: "761.395"
section_name: "A validation study."
chapter_name: "ENVIRONMENTAL PROTECTION AGENCY"
subchapter_number: "R"
subchapter_name: "TOXIC SUBSTANCES CONTROL ACT"
part_number: "761"
part_name: "POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING, DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS"
positive_law: false
currency: "2026-03-24"
last_updated: "2026-03-24"
format_version: "1.1.0"
generator: "[email protected]"
authority: "15 U.S.C. 2605, 2607, 2611, 2614, and 2616 and 42 U.S.C. 6939g."
regulatory_source: "43 FR 7156, Feb. 17, 1978, unless otherwise noted."
cfr_part: "761"
---

# 761.395 A validation study.

(a) Decontaminate the following prepared sample surfaces using the selected testing parameters and experimental conditions. Take a standard wipe sample of the decontaminated surface.

(1) At least one uncontaminated surface. The surface levels of PCBs on the uncontaminated surface must be <1 µg/100 cm
<sup>2</sup>.

(2) At least seven contaminated surfaces.

(b)(1) Select applicable method(s) from the following list to extract PCBs and determine the PCB concentration from the standard wipe sample collection medium: SW-846 Method 3540C, Method 3550C, Method 3541, Method 3545A, Method 3546, or Method 8082A (all standards incorporated by reference in § 761.19). Modifications to the methods listed in this paragraph or alternative methods not listed may be used if validated under subpart Q of this part.

(2) Report all validation study surface sample concentrations on the basis of micrograms of PCBs per 100 cm
<sup>2</sup> of surface sampled.

(c) Following completion of the validation study, measurements from the contaminated surfaces must have an arithmetic mean of ≤10 µg/100 cm
<sup>2</sup>. If the arithmetic mean is >10 µg/100 cm
<sup>2</sup>, then the validation study failed and the solvent may not be used for decontamination under § 761.79(d)(4) according to the parameters tested.

[63 FR 35473, June 29, 1998, as amended at 88 FR 59696, Aug. 29, 2023]