# Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Patent Applications Concerning Specific Inihibitors and Therapeutic Agents for Botulinum Toxin B and Tetanus Neurotoxins
**AGENCY:**
Department of the Army, DOD.
**ACTION:**
Notice.
**SUMMARY:**
In accordance with 37 CFR 404.6 and 404.7, announcement is made of the availability for licensing of the related U.S. patent applications concerning “Specific Inhibitors and therapeutic Agents for Botulinum Toxin B and Tetanus Neurotoxins” listed below. The United States Government, as represented by the Secretary of the Army, has rights in these inventions. Foreign rights are also available.
**ADDRESSES:**
Commander, U.S. Army Medical Research and Materiel Command, ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, Frederick, MD 1702-5012.
**FOR FURTHER INFORMATION CONTACT:**
For patent issues, Ms. Elizabeth Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul Mele, Office of Research & Technology Assessment, (301) 619-6664, bh at telefax (301) 619-5034.
**SUPPLEMENTARY INFORMATION:**
The following patents are available for licensing:
(1) *U.S. Patent Application No.:* 09/570,022.
*Filed:* May 12, 2000.
*Title:* Previns as Specific Inhibitors and Therapeutic Agents for Botulinum
Toxin B and Tetanus Neurotoxins.
*Supplementary Information:* The compounds of the invention may be used as molecular building blocks to create compounds that are optimized for inhibiting the protease activity of Botulinum B and tetanus toxins. Foreign rights (PCT/US00/13215) are also available.
(2) *U.S. Patent Application No.:* 09/570,023.
*Filed:* May 12, 2000.
*Title:* Buforin I as a Specific Inhibitor and Therapeutic Agent for Botulinum Toxin B and Tetanus Neurotoxins.
*Supplementary Information:* The compounds of the invention may be used to inhibit the protease activity of Botulinum B and tetanus toxins. . Foreign rights (PCT/US00/12909) are also available.
(3) *U.S. Patent Application No.:* 09/979,101.
*Filed:* November 19, 2001.
*Title:* Previns as Specific Inhibitors and Therapeutic Agents for Botulinum Toxin B and Tetanus Neurotoxins.
*Supplementary Information:* The compounds of the invention may be used as molecular building blocks to create compounds that are optimized for inhibiting the protease activity of Botulinum B and tetanus toxins. Foreign rights (PCT/US00/13215) are also available.
Luz D. Ortiz,
Army Federal Register Liaison Officer.