# Availability for Non-Exclusive, Exclusive, or Partially Exclusive Licensing of U.S. Patent Application Concerning Chemosensitizing Agents Against Choroquine Resistant P. Falciparum and Methods of Making and Using Thereof
**AGENCY:**
Department of the Army, DoD.
**ACTION:**
Notice.
**SUMMARY:**
In accordance with 37 CFR 404.6 and 404.7, announcement is made of the availability for licensing of U.S. Patent Application No. 09/849,400 entitled “Chemosensitizing Agents Against Chloroquine Resistant P. Falciparum and Methods of Making and Using Thereof,” filed May 7, 2001. Foreign rights are also available (PCT/USO1/14574). The United States Government, as represented by the Secretary of the Army, has rights in this invention.
**ADDRESSES:**
Commander, U.S. Army Medical Research and Materiel, Command, ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, Frederick, MD 21702-5012.
**FOR FURTHER INFORMATION CONTACT:**
For patent issues, Ms. Elizabeth Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul Mele, Office of Research & Technology Assessment, (301) 610-6664, both at telefax (301) 619-5034.
**SUPPLEMENTARY INFORMATION:**
A compound having the structural formula
or pharmaceutically acceptable salt or prodrug thereof, wherein X is a substituted or unsubstituted alkyl or a heteroatom; n is 4, 5 or 6; Y is a substituted or unsubsituted or alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, or
wherein R1 and R2 are each independently, H, a heteroatom, substituted or unsubstituted alkyl, cycloalkl, heterocycloalkyl, aryl, or heteroaryl; and wherein each ring structure are independently substituted or unsubsituted is disclosed. Also disclosed are chemosensitizing agents and methods of modulating, attenuating, reversing, or affecting a cell's or organism's resistance to a given drug such as an antimalarial.
Luz D. Ortiz,
Army Federal Register Liaison Officer.