Notice of Extension of Public Comment Period for the External Review Draft of a “Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility From Early-Life Exposure to Carcinogens”

---
identifier: "/us/fr/E7-22508"
source: "fr"
legal_status: "authoritative_unofficial"
title: "Notice of Extension of Public Comment Period for the External Review Draft of a “Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility From Early-Life Exposure to Carcinogens”"
title_number: 0
title_name: "Federal Register"
section_number: "E7-22508"
section_name: "Notice of Extension of Public Comment Period for the External Review Draft of a “Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility From Early-Life Exposure to Carcinogens”"
positive_law: false
currency: "2007-11-16"
last_updated: "2007-11-16"
format_version: "1.1.0"
generator: "[email protected]"
agency: "Environmental Protection Agency"
document_number: "E7-22508"
document_type: "notice"
publication_date: "2007-11-16"
agencies:
  - "Environmental Protection Agency"
fr_citation: "72 FR 64617"
fr_volume: 72
docket_ids:
  - "FRL-8496-9"
fr_action: "Notice of extension of public comment period."
---


#  Notice of Extension of Public Comment Period for the External Review Draft of a “Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility From Early-Life Exposure to Carcinogens”

**AGENCY:**

Environmental Protection Agency (EPA).

**ACTION:**

Notice of extension of public comment period.

**SUMMARY:**

On September 27, 2007, the U.S. Environmental Protection Agency (EPA) released for public comment the External Review Draft of the “Framework for Determining a Mutagenic Mode of Action for Carcinogenicity: Using EPA's 2005 *Cancer Guidelines and Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens* ” (or *Framework* ). At that time, a 60-day public comment period was announced. This notice announces a 30-day extension of the public comment period; the public comment period will end 90 days from September 27, 2007, the date of the original *Federal Register* Notice (72 FR 54910). Visit *http://www.epa.gov/fedrgstr/EPA-GENERAL/2007/September/Day-27/g19119.pdf* ) for further information. Members of the public may obtain the draft interim guidance from *http://www.regulations.gov;* or *http://www.epa.gov/osa/mmoaframework* ; or consult the person listed under *FOR FURTHER INFORMATION CONTACT* .

**ADDRESSES:**

The draft document is available electronically through the EPA Office of the Science Advisor's Web site at: *http://www.epa.gov/osa/mmoaframework* .

**FOR FURTHER INFORMATION CONTACT:**

For more information, contact Resha Putzrath, Ph.D., Office of the Science Advisor, Mail Code 8105R, U.S. Environmental Protection Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone number: (202) 564-3229; fax number: (202) 564-2070, e-mail: *[email protected]* .

Dated: November 8, 2007.

George M. Gray,

EPA Science Advisor.