21 CFR § 170.240 - Part 4 of a GRAS notice: Self-limiting levels of use.

---
identifier: "/us/cfr/t21/s170.240"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 170.240 - Part 4 of a GRAS notice: Self-limiting levels of use."
title_number: 21
title_name: "Food and Drugs"
section_number: "170.240"
section_name: "Part 4 of a GRAS notice: Self-limiting levels of use."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "B"
subchapter_name: "FOOD FOR HUMAN CONSUMPTION"
part_number: "170"
part_name: "FOOD ADDITIVES"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 341, 342, 346a, 348, 371."
regulatory_source: "42 FR 14483, Mar. 15, 1977, unless otherwise noted."
cfr_part: "170"
---


# 170.240 Part 4 of a GRAS notice: Self-limiting levels of use.

In circumstances where the amount of the notified substance that can be added to food is limited because food containing levels of the notified substance above a particular level would become unpalatable or technologically impractical, in Part 4 of your GRAS notice you must include data and information on such self-limiting levels of use.