21 CFR § 570.240 - Part 4 of a GRAS notice: Self-limiting levels of use.

---
identifier: "/us/cfr/t21/s570.240"
source: "ecfr"
legal_status: "authoritative_unofficial"
title: "21 CFR § 570.240 - Part 4 of a GRAS notice: Self-limiting levels of use."
title_number: 21
title_name: "Food and Drugs"
section_number: "570.240"
section_name: "Part 4 of a GRAS notice: Self-limiting levels of use."
chapter_name: "FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES"
subchapter_number: "E"
subchapter_name: "ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS"
part_number: "570"
part_name: "FOOD ADDITIVES"
positive_law: false
currency: "2026-04-05"
last_updated: "2026-04-05"
format_version: "1.1.0"
generator: "[email protected]"
authority: "21 U.S.C. 321, 341, 342, 346a, 348, 371."
regulatory_source: "41 FR 38644, Sept. 10, 1976, unless otherwise noted."
cfr_part: "570"
---


# 570.240 Part 4 of a GRAS notice: Self-limiting levels of use.

In circumstances where the amount of the notified substance that can be added to animal food is limited because animal food containing levels of the notified substance above a particular level would become unpalatable or technologically impractical, in Part 4 of your GRAS notice you must include data and information on such self-limiting levels of use.